Publications

PUBLICATIONS

The publication of research is not the end of a journey, but the beginning of its impact.

Full list of publications: Google Scholar

Long-acting Implants

Zhong ZY, Ren A, Doluisio N, Smith W, Qin B, Wang Y, Zhang F*, Correlation between material, structure, and drug release of Nexplanon®: an ethylene vinyl acetate based long-acting implant, International Journal of Pharmaceutics 682:125971 (2025)

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Graphical Abstract from "Zhong ZY, Ren A, Doluisio N, Smith W, Qin B, Wang Y, Zhang F*, Correlation between material, structure, and drug release of Nexplanon®: an ethylene vinyl acetate based long-acting implant, International Journal of Pharmaceutics 682:125971 (2025)"
Johnson C, Chen BB, Bhalla A, Crowell E, Zhang F*, Elimination of “lag” and “burst” phase in drug release profiles of melt-extruded PLGA-based intravitreal implants, International Journal of Pharmaceutics  681: 125822 (2025)

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Graphical Abstract from "Johnson C, Chen BB, Bhalla A, Crowell E, Zhang F*, Elimination of “lag” and “burst” phase in drug release profiles of melt-extruded PLGA-based intravitreal implants, International Journal of Pharmaceutics  681: 125822 (2025)"
Johnson C, Zhang F*, Development of a melting point depression method to measure the solubility of a small-molecule drug in PLGA, Pharmaceutical Research 42:529-543 (2025)

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Graphical Abstract from "Johnson C, Zhang F*, Development of a melting point depression method to measure the solubility of a small-molecule drug in PLGA, Pharmaceutical Research 42:529-543 (2025)"
Costello MA, Liu J, Wang Y, Bin Q, Xu XM, Li Q, Lynd NA, Zhang F*. Role of PLGA variability in controlled drug release from dexamethasone intravitreal implants, Molecular Pharmaceutics 20:6330-6334 (2023)

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Graphical Abstract from "Costello MA, Liu J, Wang Y, Bin Q, Xu XM, Li Q, Lynd NA, Zhang F*. Role of PLGA variability in controlled drug release from dexamethasone intravitreal implants, Molecular Pharmaceutics 20:6330-6334 (2023)"
Costello MA, Liu J, Wang Y, Bin Q, Xu XM, Li Q, Lynd NA, Zhang F*. Manufacturing dexamethasone intravitreal implants: process control and critical quality attributes, International Journal of Pharmaceutics 647:123515 (2023)

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Graphical Abstract from "Costello MA, Liu J, Wang Y, Bin Q, Xu XM, Li Q, Lynd NA, Zhang F*. Manufacturing dexamethasone intravitreal implants: process control and critical quality attributes, International Journal of Pharmaceutics 647:123515 (2023)"
Costello MA, Liu J, Chen BB, Wang Y, Qin B, Xu XM, Li Q, Lynd NA, Zhang F*. Drug release mechanisms of high-drug-load, melt-extruded dexamethasone intravitreal implants, European Journal of Pharmaceutics and Biopharmaceutics 187:46-56 (2023)

Link to the article

Graphical Abstract from "Costello MA, Liu J, Chen BB, Wang Y, Qin B, Xu XM, Li Q, Lynd NA, Zhang F*. Drug release mechanisms of high-drug-load, melt-extruded dexamethasone intravitreal implants, European Journal of Pharmaceutics and Biopharmaceutics 187:46-56 (2023)"

Continuous Processing Based on Twin-screw Extrusion

Pradhan A, Yang FY, Karan K, Durig T, Schwing Q, Haight B, Costelle M, Anderson M, Zhang F*, Material-sparing degradation kinetics approach for stability assessment during twin-screw melt granulation, International Journal of Pharmaceutics 674:125421 (2025)

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Graphical Abstract from "Pradhan A, Yang FY, Karan K, Durig T, Schwing Q, Haight B, Costelle M, Anderson M, Zhang F*, Material-sparing degradation kinetics approach for stability assessment during twin-screw melt granulation, International Journal of Pharmaceutics 674:125421 (2025)"
Liu T, Zhang F*. Modelling drug degradation of amorphous solid dispersion during twin-screw extrusion, European Journal of Pharmaceutics and Biopharmaceutics 190:197-205 (2023)

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Graphical Abstract from "Liu T, Zhang F*. Modelling drug degradation of amorphous solid dispersion during twin-screw extrusion, European Journal of Pharmaceutics and Biopharmaceutics 190:197-205 (2023)"
Spahn JE, Hefnawy A, Smyth H, Zhang F*. Development of a novel method for the continuous blending of carrier-based dry powder for inhalation using a co-rotating twin-screw extruder, International Journal of Pharmaceutics 623:121914 (2022)

Link to the article

Graphical Abstract from "Spahn JE, Hefnawy A, Smyth H, Zhang F*. Development of a novel method for the continuous blending of carrier-based dry powder for inhalation using a co-rotating twin-screw extruder, International Journal of Pharmaceutics 623:121914 (2022)"